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The human body and mind, in normal individuals, are inseparable. From conception, through growth and development into maturity, environmental events, influences and circumstances plus all human anatomic, biochemical, and physiologic systems make each human being unique. When human systems do not function properly, regardless of etiology, a pathological condition or disease may occur. Correct evaluation and diagnosis of any abnormal conditions or disease must be made before effective preventive or interventional therapy begins. HUMAN SYSTEMS PHARMACOLOGY ® is healthcare services, given in a clinical setting, that use naturally occuring substances or medications ("drugs") to ameliorate, mitigate, resolve, correct or "cure" abnormal or pathological systems, states, diseases or conditions.

"Human Pharmacology" is one of the basic science branches of medicine. Pharmacology is usually studied during the second year of medical school. Human pharmacology encompasses the comprehensive study of naturally occuring substances (such as digitalis leaf) or drugs when administered to human beings, regardless of route, as well as their discovery, design, uses, effects and side-effects, including potential toxicity, kinetics when administered, targets and modes of drug action, metabolism, and elimination from the human body. Pharmacologists are aware of their role in "personalized medicine" wherein patients, and their specific diseases or conditions, are understood individually (based upon the patient's personal genetics, epigenetics, etc.)


"Human Therapeutics" is defined as treatment and care to combat human disease or alleviate pain or injury. Its tools include drugs, surgery, radiation therapy, mechanical devices, diet, and psychiatry. Treatment may be active, to cure a disease (requiring no further treatment after recovery), treat it long-term, or heal a wound; symptomatic, to relieve symptoms until the immune system heals the body; supportive, to keep body functions going until the disease clears; or palliative, to minimize discomfort for patients with no chance of recovery. It almost always includes prevention, usually tertiary.. Therapeutic measures can be chosen, combined, and tailored based on accurate diagnosis to fit each patient. (Encyclopedia Britannica online)


The New Millennium has ushered in an exciting era of precise and powerul therapeutics to prevent, correct or mitigate pathological conditions or diseases. This website covers therapeutics for the more common disorders and diseases of Man most likely to be of interest or concern to primary care physicians and their patients.

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Byron L. Barksdale, M.D.
Phone: 308-532-4700
Fax: 308-534-0534

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